COAPROVEL 150/12.5MG TABLET 28'S

Product Specifications: Product Name: Co Aprovel 150/12.5 mg Tablets Pack Size: 28 tablets Form: Oral tablets Strength: Irbesartan 150mg (angiotensin II receptor antagonist) Hydrochlorothiazide 12.5mg (thiazide diuretic) Active Ingredients: Irbesartan: An angiotensin II receptor blocker (ARB) that helps to relax blood vessels and lower blood pressure by blocking the action of a hormone that causes blood vessels to constrict. Hydrochlorothiazide: A diuretic that works by reducing fluid retention in the body, decreasing blood volume and further lowering blood pressure. Indications: Hypertension: For the treatment of high blood pressure. Chronic Kidney Disease: In patients with hypertension and chronic kidney disease (especially those with diabetes), it helps reduce proteinuria (protein in the urine), which is a marker of kidney damage. Stroke and Heart Disease Prevention: Reduces the risk of stroke, heart attacks, and kidney failure by effectively lowering blood pressure. Dosage: The usual starting dose for adults is 1 tablet (150mg/12.5mg) once daily. Dosage may be adjusted based on the patient’s response and other health factors. Administration: Take 1 tablet once daily, with or without food. Swallow the tablet whole with a glass of water. Do not chew or crush the tablet. Storage: Store in a cool, dry place at room temperature (15°C–30°C). Keep out of the reach of children. Contraindications: Allergy to Irbesartan or Hydrochlorothiazide. Severe liver or kidney disease. Pregnancy and breastfeeding: Not recommended during pregnancy and should be avoided in the second and third trimesters. Severe dehydration or electrolyte imbalances. Precautions: Use with caution in patients with kidney or liver disease. Regular monitoring of kidney function is advised. Electrolyte Imbalance: Monitor for low potassium, low sodium, or dehydration during treatment. Side Effects: Common: Dizziness, headache, fatigue, dry mouth, and stomach upset. Serious: Low blood pressure, severe allergic reactions, liver problems, and electrolyte imbalances. If any serious side effects occur, discontinue use and consult your doctor immediately. Drug Interactions: Irbesartan may interact with ACE inhibitors, diuretics, and other antihypertensive medications. Hydrochlorothiazide may interact with NSAIDs, lithium, and other blood pressure medications. Inform your doctor about any other medications you are taking. Shelf Life: Always check the expiry date printed on the packaging. Do not use after this date.

Consult Your Doctor: Before starting Co Aprovel, consult your doctor if you have any liver, kidney, or heart conditions, or if you are pregnant or breastfeeding. Pregnancy and Breastfeeding: Co Aprovel is not recommended during pregnancy, especially during the second and third trimesters. Hydrochlorothiazide passes into breast milk, so consult your doctor if you are breastfeeding. Kidney or Liver Issues: Use with caution in patients with kidney or liver problems, as the medication can affect these organs. Monitor Blood Pressure: Regular monitoring of blood pressure is recommended to ensure the medication is working effectively. Dehydration and Electrolyte Imbalance: Hydrochlorothiazide can cause dehydration and electrolyte imbalances, so your doctor may monitor your potassium and sodium levels during treatment. Alcohol and Sodium Intake: Limit alcohol intake while taking Co Aprovel, as it can enhance the blood pressure-lowering effects and increase the risk of side effects. Ensure that your sodium intake remains consistent while on the medication. Avoid Sudden Discontinuation: Do not stop taking Co Aprovel suddenly, as it may cause a rise in blood pressure. Always consult your healthcare provider before discontinuing or adjusting your dosage.

Effective Blood Pressure Control: Combines two effective mechanisms to lower blood pressure, improving long-term cardiovascular health. Reduces Risk of Heart Disease: By lowering blood pressure, Co Aprovel helps reduce the risk of stroke, heart attack, and kidney damage. Convenient Dosage: 1 tablet per day, providing the benefits of both an ARB and a diuretic in a single pill. Dual Action: The combination of Irbesartan and Hydrochlorothiazide addresses blood pressure from multiple angles for more effective management. Supports Kidney Function: By reducing blood pressure, Co Aprovel helps protect kidney function, especially in patients with hypertension.

Packaging: 28 tablets per bottle, typically providing a 1-month supply. Storage: Store in a cool, dry place at room temperature (15°C – 30°C). Keep the bottle tightly closed. Shelf Life: Check the expiration date on the packaging.

Active Ingredients: Irbesartan: Irbesartan is an angiotensin II receptor blocker (ARB) that helps to lower blood pressure by blocking the effects of angiotensin II, a hormone that causes blood vessels to constrict. This results in vasodilation (widening of the blood vessels), making it easier for the heart to pump blood and lowering blood pressure. Hydrochlorothiazide (HCTZ): Hydrochlorothiazide is a thiazide diuretic that helps reduce fluid retention by increasing urine output. By reducing the blood volume, it further helps in lowering blood pressure.