GLUCOVANCE 500MG/5MG 30'S

Glucovance is a combination medication used for the treatment of type 2 diabetes mellitus when blood glucose levels cannot be adequately controlled with a single agent. It contains two active ingredients: Metformin Hydrochloride (500 mg): A biguanide that lowers blood glucose primarily by reducing hepatic glucose production, improving insulin sensitivity, and decreasing intestinal absorption of glucose. Glibenclamide (5 mg): A sulfonylurea that stimulates the pancreas to release more insulin, thereby lowering blood sugar levels. Together, these components offer a complementary approach to managing blood sugar, helping patients achieve better glycemic control. Glucovance is typically prescribed when monotherapy with metformin or sulfonylurea is insufficient. The tablets are taken orally, usually once or twice daily with meals to reduce gastrointestinal side effects and the risk of hypoglycemia caused by glibenclamide. Patients should follow their healthcare provider’s instructions carefully and maintain regular monitoring of blood glucose and kidney function. Glucovance is not suitable for patients with severe kidney or liver impairment, or those with a history of lactic acidosis. Caution is advised when using this medication in elderly patients or those with other health conditions. Common side effects may include gastrointestinal discomfort, mild hypoglycemia, or allergic reactions. Patients are advised to seek medical attention if they experience severe symptoms such as persistent low blood sugar, lactic acidosis symptoms, or allergic reactions.