🧴 Step-by-Step Instructions 🔹 Initial (Treatment) Phase – 2 Months Cleanse your face with a gentle, non-foaming cleanser. Dry your skin completely (do not apply to wet skin to avoid irritation). Apply a small amount of Metroruboril A.Z to affected areas (or entire face if needed). Use twice daily – morning and evening. 🔹 Maintenance Phase (after 2 months) Use it once daily in the evening. In the morning, switch to a calming moisturizer (like Ruboril Expert S or M) and SPF 50+ sunscreen. 💡 Usage Tips Patch test before first use to ensure skin tolerance. Expect a mild tingling or warming sensation in the first few days—this usually fades. Avoid layering with other strong actives (like AHAs, BHAs, or retinoids) unless your skin is well-adjusted. Use sun protection daily to prevent further redness and pigmentation. 🚫 Avoid If: You’re applying it over broken or irritated skin. You’re using strong exfoliants or retinoids without guidance. You’re applying to wet/damp skin (increases irritation risk).
Specification Details Product Name Isis Pharma Metroruboril A.Z Anti-Redness Cream Brand Isis Pharma Size 30 ml Type Facial Cream / Dermatological Treatment Formulation Cream-gel texture, lightweight and non-greasy Key Active Ingredient Azelaic Acid 15% Secondary Actives β-CALM® complex (Niacinamide, Betaine, Panthenol, Centella, Escin, etc.) Target Concerns Facial redness, rosacea, inflammatory papules and pustules, PIH/PIE Skin Types All skin types; especially sensitive and redness-prone Suitable For Adults; safe for use during pregnancy and breastfeeding Fragrance Fragrance-free Color White to off-white Application Area Face (targeted or full-face use) Usage Frequency 1–2 times daily (depending on phase and tolerance) Sun Sensitivity Does not increase sun sensitivity significantly, but SPF is still required Shelf Life Usually 12–24 months from opening (check packaging) Storage Store in a cool, dry place away from direct sunlight Packaging Plastic squeeze tube with screw or flip cap Made In France
✅ Do: Perform a patch test before first use — apply a small amount on your inner forearm and wait 24 hours. Apply only to clean, dry skin to reduce risk of irritation. Use sun protection (SPF 50+) during the day while using this product to prevent sensitivity or pigmentation. Follow recommended usage: Twice daily for 2 months (initial phase) Then once daily at night (maintenance phase) Store at room temperature, away from direct sunlight and heat. 🚫 Avoid: Applying on broken, irritated, or sunburned skin Using on wet or damp skin (may increase stinging or burning) Mixing or layering with: Strong exfoliants (AHAs, BHAs) Retinoids (unless under professional guidance) Contact with eyes, mucous membranes, or inside the nose. If contact occurs, rinse thoroughly with water. Over-applying — a thin, even layer is sufficient. ⚠️ Possible Side Effects (usually temporary): Mild tingling or stinging in the first few days Slight peeling or redness (especially in sensitive skin types or when used with other actives) Very rare: allergic reaction (rash, swelling, itching) — discontinue use and consult a doctor 👩⚕️ Safe For: Sensitive and rosacea-prone skin Pregnant or breastfeeding women (per manufacturer) Daily long-term use (with proper cycling and sun protection)
🌟 Top Benefits ✅ 1. Reduces Facial Redness Formulated with 15% ultra-pure azelaic acid, known for calming visible redness and inflammation. Helps relieve symptoms of rosacea, flushing, and blotchiness. ✅ 2. Targets Blemishes & Pustules Clinical tests show up to: 60% reduction in papules 88% reduction in pustules Effective for acne-like rosacea and inflammatory breakouts. ✅ 3. Soothes & Calms Irritation The β‑CALM® complex (niacinamide, centella asiatica, calendula, glycyrrhetinic acid) provides strong anti-inflammatory and barrier-repair effects. Reduces stinging, dryness, and itchiness often associated with rosacea or sensitive skin. ✅ 4. Strengthens Skin Barrier & Microcirculation Improves the function of skin capillaries and reinforces vessel walls (with plant extracts like horse chestnut, ruscus, and yeast proteins). Helps prevent future flare-ups and skin reactivity. ✅ 5. Safe for Sensitive & Rosacea-Prone Skin Fragrance-free, non-comedogenic, and dermatologically tested. Approved for use during pregnancy and breastfeeding. ✅ 6. Non-Oily, Lightweight Texture Cream-gel format absorbs quickly, leaves a matte finish. No greasy residue — ideal under makeup or sunscreen. ✅ 7. Visible Results in Weeks Many users report improvements in redness and skin texture within 2–4 weeks. Well tolerated even with long-term use.
✅ Patch test before first use — apply a small amount to inner forearm or behind the ear and wait 24 hours for reaction. ✅ Always apply only to clean, dry skin — applying it on damp skin increases absorption and potential irritation. Amazon ✅ Morning & evening application is recommended during initial 2–3 months if treating widespread imperfections. For localized use, apply only at night, with a soothing moisturizer in AM. ❌ Avoid using on broken or severely irritated skin, and do not apply near eyes or mucous membranes. If contact occurs, rinse thoroughly. ✅ Compatible with pregnant or breastfeeding women; fragrance-free and dermatologically tested for sensitive skin types. ⚠️ Slight tingling or warming sensation may occur initially; this typically subsides with continued use. Nahdi Online Pharmacy Isispharma
Per official brand and distributor sources, the full ingredient list is: Aqua (Water), Azelaic Acid, Betaine, Caprylic/Capric Triglyceride, Glycerin, Butylene Glycol, Pentylene Glycol, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Lauryl Glucoside, Polyglyceryl‑2 Dipolyhydroxystearate, Glycyrrhetinic Acid, Niacinamide, Ethylhexylglycerin, Panthenol, Sclerotium Gum, Chlorphenesin, Escin, O‑Cymen‑5‑Ol, Polysorbate 60, Sorbitan Isostearate, Ruscus Aculeatus (Butcher’s‑Broom) Root Extract, Ammonium Glycyrrhizate, Citric Acid, Centella Asiatica Leaf Extract, Hydrolyzed Yeast Protein, Calendula Officinalis Flower Extract, Sodium Citrate