TRULICITY 1.5MG SOLN FOR INJECTION PEN 4'S

Parameter Details Brand Name Trulicity Generic Name Dulaglutide Strength 1.5 mg per 0.5 mL Form Solution for injection Presentation Pre-filled single-dose pen (autoinjector), 4 pens per box Drug Class GLP-1 receptor agonist (glucagon-like peptide-1 analogue) Route of Administration Subcutaneous injection (abdomen, thigh, or upper arm) Indication Type 2 diabetes mellitus (for blood sugar control and cardiovascular risk reduction) Dose Frequency Once weekly Onset of Action Within a few days; full effect over weeks Storage Conditions Refrigerate at 2°C – 8°C; can be kept at room temp (≤30°C) for 14 days Shelf Life Usually 2 years unopened; check label for expiry Manufacturer Eli Lilly and Company

1. ✅ Before You Start Using Trulicity Use only as prescribed by your doctor for Type 2 diabetes. Do not use if you: Have Type 1 diabetes or diabetic ketoacidosis (DKA) Have a personal or family history of medullary thyroid cancer (MTC) or MEN 2 (Multiple Endocrine Neoplasia syndrome type 2) Are pregnant or breastfeeding, unless advised by your doctor 2. 💉 Proper Use of the Injection Use only once per week, on the same day each week. Inject subcutaneously (under the skin) in the abdomen, thigh, or upper arm. Do not inject into a muscle or vein. Do not share your pen with anyone—even if the needle has been changed (infection risk). 3. ⚠️ Watch for Side Effects Common (usually mild): nausea, vomiting, diarrhea, loss of appetite, fatigue. Serious (seek immediate help): Severe abdominal pain (possible pancreatitis) Signs of allergic reaction: swelling, rash, difficulty breathing Low blood sugar (hypoglycemia): especially if used with insulin or sulfonylureas Kidney problems from dehydration (due to vomiting or diarrhea) 4. 🧪 Monitoring During Use Regularly monitor: Blood glucose levels Kidney function (especially if dehydrated) Thyroid swelling or hoarseness (report any neck lumps or difficulty swallowing) 5. 🧊 Storage Safety Store in the refrigerator (2–8°C); do not freeze. If needed, store at room temperature (below 30°C) for up to 14 days. Protect from light, and keep the pen in the original carton. Discard expired or damaged pens safely. 6. 🚫 Missed Dose Instructions If you miss a dose, inject it within 3 days. If more than 3 days have passed, skip the missed dose and continue with your next scheduled injection. Do not take two doses at the same time.

1. Effective Blood Sugar Control Helps lower HbA1c levels (a long-term measure of blood glucose). Particularly effective for Type 2 diabetes patients who haven't achieved control with oral medications. 2. Convenient Weekly Dosing Only one injection per week, making it easier to adhere to compared to daily injections. Pre-filled, single-use pens are easy to use—no mixing or measuring required. 3. Supports Weight Loss Many users experience reduced appetite and gradual weight loss, which is beneficial for insulin sensitivity and cardiovascular health. 4. Low Risk of Hypoglycemia Because it works only when blood sugar levels are elevated, the risk of hypoglycemia is lower—especially when not used with insulin or sulfonylureas. 5. Cardiovascular Protection In people with type 2 diabetes and existing heart disease, Trulicity has shown benefits in reducing the risk of heart attack, stroke, or cardiovascular death. 6. Improves Pancreatic Function Stimulates insulin secretion in response to meals. Helps suppress excess glucagon, a hormone that raises blood sugar. 7. Once-Weekly Routine Reduces Daily Burden Encourages better long-term adherence for people managing chronic conditions.

What Trulicity Is Used For Trulicity (dulaglutide) is used to improve blood sugar control in adults with Type 2 diabetes. It may also be prescribed to reduce the risk of major cardiovascular events (like heart attack or stroke) in adults with diabetes and established heart disease. 🧠 How It Works It mimics a natural hormone called GLP-1 (glucagon-like peptide-1). It helps regulate blood sugar by: Stimulating insulin release after meals Suppressing glucagon (a hormone that raises blood sugar) Slowing stomach emptying, which reduces appetite and glucose spikes

Component Description Active Ingredient Dulaglutide – 1.5 mg per 0.5 mL Pharmacological Class GLP-1 receptor agonist (glucagon-like peptide-1 analogue) Form Clear, colourless solution in a pre-filled, single-use pen Concentration 1.5 mg/0.5 Ml